precision-fermentation

Precision Fermentation

The main distinction between precision fermentation and general fermentation is that the microorganisms used in precision fermentation, are designed to create a particular end product. Precision is a more advanced kind of metabolic fermentation, where living organisms convert organic chemicals from the feed stock into usable components. With the help of certain enzymes, a lot of biomass is produced, the microbes are multiplied and bred in small factories. The target product is recovered and refined to produce a functional product once a critical mass has been reached. One application of this kind of fermentation is the production of chymosin, a type of rennet that is used to  make cheese. It uses organisms such as yeast to produce pure dairy or egg proteins or ingredients such as heme.

 

Short definition:

Precisely designed microbes to produce specific ingredients.

 

Key features:

  1. Host usually not present in the final product
  2. Uses novel inexpensive feedstocks to produce high value ingredients (e.g., byproduct to produce proteins)
  3. High purity-purification step

 

Product examples:

Protein and Non-protein molecules (flavouring agents, vitamins, pigments, fats, antioxidants).

 

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https://www.forbes.com/sites/errolschweizer/2022/03/02/what-should-consumers-be-asking-about-precision-fermentation/

 

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